The Cecal Ligation and Puncture (C.L.P.) model is a widely used in vivo method for inducing polymicrobial sepsis in mice. By surgically ligating and puncturing the cecum, the model closely replicates key aspects of human sepsis and is commonly used to evaluate disease...
The cost of an in vivo infection model is influenced by several key variables, including the number and strain of animals used, housing requirements, study duration, dosing routes, and the type and frequency of data collected. Each of these factors impacts labor,...
