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Blog
Risk Factors for Asymptomatic C. difficile Colonization
Patients with asymptomatic C. difficile colonization are gaining attention as a potential source of transmission. Scientists at the Cleveland Clinic recently conducted a systematic review and meta-analysis of 19 studies published between 1975 and 2020 in order to evaluate the risk factors for asymptomatic C. difficile colonization among adults.
A New Resource to “SPARK” Antibiotic Research
One of many barriers to the discovery of novel antibiotics is a lack of information sharing. Although antibiotic research has been underway since the discovery of penicillin in 1928, it is difficult for scientists to build on past work and avoid repeating the same...
Industry in Michigan
Detroit may be known as the Motor City due to the Big Three car manufacturers that call it home, but the automotive industry isn’t the only one booming in Michigan. The life sciences have seen significant growth in recent years and the field has become one of the...
Positive Uses for Fungi
When we think of fungi, yeast and mold are likely the first to come to mind, often with negative connotations. But fungi play important roles in many areas of our lives, including many positive uses. Fungi are necessary for many of our favorite foods and beverages....
Risk Factors for C. auris colonization
A recent study out of New York has demonstrated an association among ventilator use, acute care hospital admission, and colonization with Candida auris. Colonization increases the risk for severe infection and the likelihood of transmission to other patients.
Fungi and New Drugs
A team of scientists in the Netherlands has created a giant library of compounds derived from the excretions of over 10,000 species of fungi. Each of the isolated compounds was screened for biological activity in zebrafish embryos, which were chosen due to their similarities to humans, but also because they develop nearly all of their organs quickly and simultaneously. This meant that any effects the compounds had could be observed in just a few days’ time on a wide range of cell types.
Common Delays During the Preclinical Phase
Advancing a novel therapeutic from research and discovery to clinical trials and the market is an expensive and time-consuming process. Every failed candidate can cost the company money and their reputation. Therefore, it’s important to stay on track throughout the drug development pipeline. Preventing delays during the preclinical phase is particularly critical for success.
Antibiotics in Wasp Venom
Most people do their best to avoid wasps because of the insects’ stingers, sharp self-defense organs which can pierce the skin and inject a painful and irritating venom. Yet while summer beachgoers have been running from wasps, scientists have been seeking them out.
Kombucha and Microbes
Kombucha is all the rage lately, with many considering it the latest and greatest health and energy drink. But what exactly is it? And what evidence is there to support these claims? Kombucha is a fermented tea that originated in East Asia around 2000 years ago. Brewed tea and sugar are combined with a symbiotic culture of bacteria and yeast (SCOBY) and allowed to ferment. What results is a carbonated beverage with a low alcohol content (<0.5%) and a slightly acidic, vinegary flavor.
Global Animal Model Market Predictions
According to a recent study, the global animal model market is expected to grow at an impressive rate over the next seven years with a predicted annual revenue of over $2.2 billion by the end of 2026. Mice and rats are expected to be the most lucrative research species, with more than 40% of that revenue coming from research using rodents. Further, North America is projected to remain the largest market of animal models, while contract research organizations and biotechnology companies are likely to be fastest-expanding users of research animals.




