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TransPharm Preclinical Solutions
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AZD9773 Anti-TNF-α Immune Fab in Murine CLP Sepsis
Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-a (TNF-a) using AZD9773, an anti-TNF-a immune Fab, in…
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Trick and Treat Bacteria
What do the ancient Greeks and a group of modern-day researchers have in common? Scientists at the University of Washington School of Medicine are…
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E. coli in Retail Poultry May Cause UTIs
Foodborne bacteria are a common cause of gastrointestinal infection, but a recent study found that a strain of E. coli in retail chicken and turkey…
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Summer 2018 Newsletter
We're not mousing around...TransPharm now has a blog! Stay up-to-date on the latest in microbiology, infectious disease, and antimicrobial resistance…
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Synergistic Combination Therapy Against Resistant Pathogens
Due to increasing rates of antimicrobial resistance, scientists are researching the potential of combination therapy (two or more drugs used…
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Trained Dog Can Detect C. difficile
The nose knows! A dog in British Columbia, Canada has been trained to detect Clostridium difficile. C. difficile has a very particular odor, and a…
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NDM-1 and Drug Resistance
NDM-1 is a gene that codes for New Delhi metallo-beta-lactamase 1, an enzyme that provides resistance to multiple classes of antibiotics, including…
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Preclinical Research in Drug Development
Preclinical studies provide data about drug safety and efficacy in animals to determine if the drug should proceed to clinical testing in humans…
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Economic Forecast for Preclinical CROs
Research and development (R&D), as well as manufacturing, are often outsourced from big pharma to smaller contract research organizations (CRO) with…
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These Pathogens Can ESKAPE Most Antibiotics
Antimicrobial resistance poses an ever-increasing healthcare threat, with pathogens evolving resistance faster than novel therapies are being…
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