GI Infection Models for C. difficile Infection Studies Clostridioides difficile infection (CDI) preclinical research uses murine models to study gut microbiome disruption, pathogen behavior, and immune responses. These studies are essential for developing effective...
Custom Infection Model Development: What to Expect Before beginning in vivo efficacy work with a new client at TransPharm Preclinical Solutions, we usually offer to run a validation study first. This is useful because it allows us to reaffirm the stability and...
Why TransPharm Preclinical Solutions’ Infection Models Reduce Study Risk Reducing study risks requires a proactive and systematic approach that prioritizes preparation, collaboration, and accountability. TransPharm minimizes potential risks by carefully...
Translating In Vitro Results into In Vivo Success In vitro assays such as minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and time-kill studies provide foundational data on antimicrobial potency and killing kinetics. These metrics...
. What is the Osteomyelitis Rat Model Our Osteomyelitis Rat Model is unique in that it is non-surgical in its approach. We use female Sprague Dawley rats weighing 200-225 g. Animals are anesthetized with isoflourance (induced at 5% in an induction chamber and...
