Why TransPharm Preclinical Solutions’ Infection Models Reduce Study Risk Reducing study risks requires a proactive and systematic approach that prioritizes preparation, collaboration, and accountability. TransPharm minimizes potential risks by carefully...
Translating In Vitro Results into In Vivo Success In vitro assays such as minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and time-kill studies provide foundational data on antimicrobial potency and killing kinetics. These metrics...
. What is the Osteomyelitis Rat Model Our Osteomyelitis Rat Model is unique in that it is non-surgical in its approach. We use female Sprague Dawley rats weighing 200-225 g. Animals are anesthetized with isoflourance (induced at 5% in an induction chamber and...
What are in vivo infectious disease in vivo models? An infectious disease in vivo model is a research system in which animals are experimentally infected with a pathogen to study disease progression, host immune responses, and therapeutic interventions. These models...
Why Model Validation Matters Validating in vivo models is critical in preclinical infectious disease research. Model validation improves translatability to human disease, ensures experimental reproducibility, and enables accurate assessment of antimicrobial...
Why Rodent Models Are Critical in Infectious Disease R&D In vivo infection models typically use rodent models because they are cheap, easy to house and work with, require fewer regulations to use, and for ease of euthanasia. TransPharm Preclinical Solutions uses...
