Why TransPharm Preclinical Solutions' Infection Models Reduce Study Risk Reducing study risks requires a proactive and systematic approach that prioritizes preparation, collaboration, and accountability. TransPharm minimizes potential risks by carefully reviewing...

Translating In Vitro Results into In Vivo Success  In vitro assays such as minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and time-kill studies provide foundational data on antimicrobial potency and killing kinetics. These metrics...

. What is the Osteomyelitis Rat Model Our Osteomyelitis Rat Model is unique in that it is non-surgical in its approach.  We use female Sprague Dawley rats weighing 200-225 g. Animals are anesthetized with isoflourance (induced at 5% in an induction chamber and...

What are in vivo infectious disease in vivo models? An infectious disease in vivo model is a research system in which animals are experimentally infected with a pathogen to study disease progression, host immune responses, and therapeutic interventions.  These models...

Why Model Validation Matters Validating in vivo models is critical in preclinical infectious disease research. Model validation improves translatability to human disease, ensures experimental reproducibility, and enables accurate assessment of antimicrobial...

Why Rodent Models Are Critical in Infectious Disease R&D In vivo infection models typically use rodent models because they are cheap, easy to house and work with, require fewer regulations to use, and for ease of euthanasia. TransPharm Preclinical Solutions uses...

The Best In Vivo Infection Models and Why They Matter in vivo infection models are different from an in vitro infection model in that it uses live animals as the test subject, instead of an agar plate or 96 well plate. The drug development process typically begins...

Animal Welfare: AAALAC, AALAS, & PHS assurance Animal welfare plays a critical role in scientific research, education, and biomedical advancement. Ethical treatment of animals is not only a moral responsibility but also essential for producing reliable, high...

Pneumonia Models for MDR Lung Infections Multidrug-resistant (MDR) lung infections present a growing global health threat, driving urgent demand for better preclinical models.  Pneumonia models have emerged as crucial platforms for studying host-pathogen interactions,...